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1

Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease-modifying antirheumatic drugs: The tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study

Mark C. Genovese, James D. McKay, Evgeny L. Nasonov, Eduardo F. Mysler, Nilzio A. da Silva, Emma Alecock, Thasia Woodworth, Juan J. Gomez-Reino

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 148 KB

english, 2008

2

Biosimilars in rheumatology: a view from Latin America

Mysler, Eduardo, Scheinberg, Morton

Journal:

Clinical Rheumatology

Year:

2012

Language:

english

File:

PDF, 66 KB

english, 2012

3

Biopharmaceuticals for rheumatic diseases in Latin America, Europe, Russia, and India: Innovators, biosimilars, and intended copies

Castañeda-Hernández, Gilberto, Szekanecz, Zoltan, Mysler, Eduardo, Azevedo, Valderilio F., Guzman, Renato, Gutierrez, Miguel, Rodríguez, Wilfredo, Karateev, Dmitry

Journal:

Joint Bone Spine

Year:

2014

Language:

english

File:

PDF, 580 KB

english, 2014

4

Evaluating upadacitinib for the treatment of rheumatoid arthritis

Mysler, Eduardo, Lizarraga, Ana

Journal:

Expert Opinion on Pharmacotherapy

Year:

2020

File:

PDF, 1.59 MB

2020

5

Ciprofloxacin reactions mimicking lupus flares

Eduardo Mysler, Stephen A. Paget, Robert Kimberly

Journal:

Arthritis & Rheumatism

Year:

1994

Language:

english

File:

PDF, 234 KB

english, 1994

6

Levels of soluble fas/APO-1 /CD95 in systemic lupus erythematosus and juvenile rheumatoid arthritis

Eckart Knipping, Peter H. Krammer, Karen B. Onel, Thomas J. A. Lehman, Eduardo Mysler, Keith B. Elkon

Journal:

Arthritis & Rheumatism

Year:

1995

Language:

english

File:

PDF, 304 KB

english, 1995

7

Prevalence of positive ppd in a cohort of rheumatoid arthritis patients

Maria Natalia Tamborenea, Guillermo Tate, Eduardo Mysler, Jose Debonis, Adrian Schijedman

Journal:

Rheumatology International

Year:

2010

Language:

english

File:

PDF, 199 KB

english, 2010

8

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial

Thomas J Schnitzer, Gerd R Burmester, Eduardo Mysler, Marc C Hochberg, Michael Doherty, Elena Ehrsam, Xavier Gitton, Gerhard Krammer, Bernhard Mellein, Patrice Matchaba, Alberto Gimona, Christopher J

Journal:

Year:

2004

Language:

english

File:

PDF, 126 KB

english, 2004

9

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial

Michael E Farkouh, Howard Kirshner, Robert A Harrington, Sean Ruland, Freek WA Verheugt, Thomas J Schnitzer, Gerd R Burmester, Eduardo Mysler, Marc C Hochberg, Michael Doherty, Elena Ehrsam, Xavier Gi

Journal:

Year:

2004

Language:

english

File:

PDF, 118 KB

english, 2004

10

Efficacy and Safety of Ocrelizumab in Active Proliferative Lupus Nephritis: Results From a Randomized, Double-Blind, Phase III Study

Mysler, Eduardo F., Spindler, Alberto J., Guzman, Renato, Bijl, Marc, Jayne, David, Furie, Richard A., Houssiau, Frédéric A., Drappa, Jorn, Close, David, Maciuca, Romeo, Rao, Kajal, Shahdad, Saba, Bru

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 148 KB

english, 2013

11

Work instability in rheumatoid arthritis patients from Argentina: prevalence and associated factors

Tamborenea, Maria N., Pisoni, Cecilia, Toloza, Sergio, Mysler, Eduardo, Tate, Guillermo, Pereira, Dora, García Carrasco, M., Quintero, J., Cappuccio, A., Granel, A., Lazaro, M., Arturi, Pablo, Citera,

Journal:

Rheumatology International

Year:

2015

Language:

english

File:

PDF, 211 KB

english, 2015

12

The effect of antidrug antibodies on the sustainable efficacy of biologic therapies in rheumatoid arthritis: practical consequences

Keiserman, Mauro, Codreanu, Catalin, Handa, Rohini, Xibillé-Friedmann, Daniel, Mysler, Eduardo, Briceño, Francisco, Akar, Servet

Journal:

Expert Review of Clinical Immunology

Year:

2014

Language:

english

File:

PDF, 303 KB

english, 2014

13

Biothérapies en rhumatologie en Amérique Latine, en Europe, en Russie et en Inde : produits innovants, biosimilaires et prétendues copies

Castañeda-Hernández, Gilberto, Szekanecz, Zoltan, Mysler, Eduardo, Azevedo, Valderilio F., Guzman, Renato, Gutierre, Miguel, Rodríguez, Wilfredo, Karateev, Dmitry

Journal:

Revue du Rhumatisme

Year:

2015

Language:

french

File:

PDF, 528 KB

french, 2015

14

Biosimilars: Clinical Interpretation and Implications for Drug Development

Mysler, Eduardo

Journal:

Current Rheumatology Reports

Year:

2015

Language:

english

File:

PDF, 751 KB

english, 2015

15

Sifalimumab, a Human Anti-Interferon-α Monoclonal Antibody, in Systemic Lupus Erythematosus: A Phase I Randomized, Controlled, Dose-Escalation Study

Petri, Michelle, Wallace, Daniel J., Spindler, Alberto, Chindalore, Vishala, Kalunian, Kenneth, Mysler, Eduardo, Neuwelt, C. Michael, Robbie, Gabriel, White, Wendy I., Higgs, Brandon W., Yao, Yihong,

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 432 KB

english, 2013

16

Clinical and regulatory perspectives on biosimilar therapies and intended copies of biologics in rheumatology

Mysler, Eduardo, Pineda, Carlos, Horiuchi, Takahiko, Singh, Ena, Mahgoub, Ehab, Coindreau, Javier, Jacobs, Ira

Journal:

Rheumatology International

Year:

2016

Language:

english

File:

PDF, 607 KB

english, 2016

17

The Efficacy and Safety of Subcutaneous Clazakizumab in Patients With Moderate-to-Severe Rheumatoid Arthritis and an Inadequate Response to Methotrexate: Results From a Multinational, Phase IIb, Randomized, Double-Blind, Placebo/Active-Controlled, Dose-Ra

Weinblatt, Michael E., Mease, Philip, Mysler, Eduardo, Takeuchi, Tsutomu, Drescher, Edit, Berman, Alberto, Xing, Jun, Zilberstein, Moshe, Banerjee, Subhashis, Emery, Paul

Journal:

Arthritis & Rheumatology

Year:

2015

Language:

english

File:

PDF, 366 KB

english, 2015

18

A randomised phase IIb study of mavrilimumab, a novel GM–CSF receptor alpha monoclonal antibody, in the treatment of rheumatoid arthritis

Burmester, Gerd R, McInnes, Iain B, Kremer, Joel, Miranda, Pedro, Korkosz, Mariusz, Vencovsky, Jiri, Rubbert-Roth, Andrea, Mysler, Eduardo, Sleeman, Matthew A, Godwood, Alex, Sinibaldi, Dominic, Guo,

Journal:

Annals of the Rheumatic Diseases

Year:

2017

Language:

english

File:

PDF, 1.54 MB

english, 2017

19

Safety of Tofacitinib in the Treatment of Rheumatoid Arthritis in Latin America Compared With the Rest of the World Population

Castañeda, Oswaldo M., Romero, Felix J., Salinas, Ariel, Citera, Gustavo, Mysler, Eduardo, Rillo, Oscar, Radominski, Sebastiao C., Cardiel, Mario H., Jaller, Juan J., Alvarez-Moreno, Carlos, Ponce de

Journal:

JCR Journal of Clinical Rheumatology

Year:

2017

Language:

english

File:

PDF, 781 KB

english, 2017

20

Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-to-head, randomised controlled trial

Fleischmann, Roy, Mysler, Eduardo, Hall, Stephen, Kivitz, Alan J, Moots, Robert J, Luo, Zhen, DeMasi, Ryan, Soma, Koshika, Zhang, Richard, Takiya, Liza, Tatulych, Svitlana, Mojcik, Christopher, Krishn

Journal:

Year:

2017

Language:

english

File:

PDF, 661 KB

english, 2017

21

Switching Between Reference Biologics and Biosimilars for the Treatment of Rheumatology, Gastroenterology, and Dermatology Inflammatory Conditions: Considerations for the Clinician

Moots, Robert, Azevedo, Valderilio, Coindreau, Javier L., Dörner, Thomas, Mahgoub, Ehab, Mysler, Eduardo, Scheinberg, Morton, Marshall, Lisa

Journal:

Current Rheumatology Reports

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

22

Body mass index and clinical response to intravenous or subcutaneous abatacept in patients with rheumatoid arthritis

D’Agostino, Maria-Antonietta, Alten, Rieke, Mysler, Eduardo, Le Bars, Manuela, Ye, June, Murthy, Bindu, Heitzmann, Julia, Vadanici, Radu, Ferraccioli, Gianfranco

Journal:

Clinical Rheumatology

Year:

2017

Language:

english

File:

PDF, 574 KB

english, 2017

23

Etanercept for the treatment of rheumatoid arthritis

Zhao, Sizheng, Mysler, Eduardo, Moots, Robert J

Journal:

Year:

2018

Language:

english

File:

PDF, 832 KB

english, 2018

24

Longterm Safety and Efficacy of Subcutaneous Abatacept in Patients with Rheumatoid Arthritis: 5-year Results from a Phase IIIb Trial

Genovese, Mark C., Pacheco-Tena, César, Covarrubias, Arturo, Leon, Gustavo, Mysler, Eduardo, Keiserman, Mauro, Valente, Robert M., Nash, Peter, Simon-Campos, J. Abraham, Box, Jane, Legerton, Clarence

Journal:

The Journal of Rheumatology

Year:

2018

Language:

english

File:

PDF, 802 KB

english, 2018

25

O22. Efficacy and Safety of Subcutaneous Versus Intravenous Tocilizumab In Combination with Traditional Dmards in Patients with Rheumatoid Arthritis: 49 Week Summacta Data

Burmester, Gerd R., Rubbert-Roth, Andrea, Cantagrel, Alain, Hall, Stephen, Leszczyński, Piotr, Feldman, Daniel, Rangaraj, Madura J., Roane, Georgia, Ludivico, Charles, Mysler, Eduardo F., Wells, Chris

Journal:

Year:

2014

Language:

english

File:

PDF, 30 KB

english, 2014

26

Efficacy and Safety Outcomes for Originator TNF Inhibitors and Biosimilars in Rheumatoid Arthritis and Psoriasis Trials: A Systematic Literature Review

Moots, Robert J., Curiale, Cinzia, Petersel, Danielle, Rolland, Catherine, Jones, Heather, Mysler, Eduardo

Journal:

Year:

2018

Language:

english

File:

PDF, 518 KB

english, 2018

27

Review of Biosimilar Trials and Data on Adalimumab in Rheumatoid Arthritis

Zhao, Sizheng, Chadwick, Laura, Mysler, Eduardo, Moots, Robert J.

Journal:

Current Rheumatology Reports

Year:

2018

Language:

english

File:

PDF, 1.69 MB

english, 2018

28

Review of Biosimilar Trials and Data on Etanercept in Rheumatoid Arthritis

Chadwick, Laura, Zhao, Sizheng, Mysler, Eduardo, Moots, Robert J.

Journal:

Current Rheumatology Reports

Year:

2018

Language:

english

File:

PDF, 1.67 MB

english, 2018

29

214. BODY MASS INDEX DOES NOT AFFECT RESPONSE TO SUBCUTANEOUS OR INTRAVENOUS ABATACEPT IN PATIENTS WITH RHEUMATOID ARTHRITIS

D’Agostino, Maria-Antonietta, Alten, Rieke, Mysler, Eduardo, Le Bars, Manuela, Ye, June, Murthy, Bindu, Heitzmann, Julia, Vadanici, Radu, Ferraccioli, Gianfranco

Journal:

Year:

2017

File:

PDF, 76 KB

2017

30

Upadacitinib versus Placebo or Adalimumab in Patients with Rheumatoid Arthritis and an Inadequate Response to Methotrexate: Results of a Phase 3, Double‐Blind, Randomized Controlled Trial

Fleischmann, Roy, Pangan, Aileen L, Song, In‐Ho, Mysler, Eduardo, Bessette, Louis, Peterfy, Charles, Durez, Patrick, Ostor, Andrew J, Li, Yihan, Zhou, Yijie, Othman, Ahmed A, Genovese, Mark C

Journal:

Arthritis & Rheumatology

Year:

2019

Language:

english

File:

PDF, 1.19 MB

english, 2019

31

Safety and effectiveness of upadacitinib or adalimumab plus methotrexate in patients with rheumatoid arthritis over 48 weeks with switch to alternate therapy in patients with insufficient response

Fleischmann, Roy M, Genovese, Mark C, Enejosa, Jeffrey V, Mysler, Eduardo, Bessette, Louis, Peterfy, Charles, Durez, Patrick, Ostor, Andrew, Li, Yihan, Song, In-Ho

Journal:

Annals of the Rheumatic Diseases

Year:

2019

Language:

english

File:

PDF, 487 KB

english, 2019

32

Patient-reported outcomes for tofacitinib with and without methotrexate, or adalimumab with methotrexate, in rheumatoid arthritis: a phase IIIB/IV trial

Strand, Vibeke, Mysler, Eduardo, Moots, Robert J, Wallenstein, Gene V, DeMasi, Ryan, Gruben, David, Soma, Koshika, Iikuni, Noriko, Smolen, Josef S, Fleischmann, Roy

Journal:

Year:

2019

Language:

english

File:

PDF, 1.23 MB

english, 2019

33

Nonmedical Switching From Originators to Biosimilars: Does the Nocebo Effect Explain Treatment Failures and Adverse Events in Rheumatology and Gastroenterology?

Fleischmann, Roy, Jairath, Vipul, Mysler, Eduardo, Nicholls, Dave, Declerck, Paul

Journal:

Rheumatology and Therapy

Year:

2020

File:

PDF, 886 KB

2020

34

P200âCharacterisation of remission in patients with rheumatoid arthritis treated with upadacitinib or comparators

Hall, Stephen, Takeuchi, Tsutomu, Thomson, Glen, Emery, Paul, Combe, Bernard, Everding, Andrea, Pavelka, Karel, Song, Yanna, Shaw, Tim, Friedman, Alan, Song, In-Ho, Mysler, Eduardo

Journal:

Year:

2020

File:

PDF, 64 KB

2020

35

P225âInhibition of structural joint damage with upadacitinib as monotherapy or in combination with MTX in patrients with RA: one-year outcomes from the select Phase 3 programme

Peterfy, Charles, Genovese, Mark C, Song, In-Ho, Friedman, Alan, Hall, Stephen, Mysler, Eduardo, Durez, Patrick, Baraliakos, Xenofon, Enejosa, Jose Jeffrey, Shaw, Tim, Li, Yihan, Chen, Su, Strand, Vib

Journal:

Year:

2020

File:

PDF, 64 KB

2020

36

Subcutaneous Tocilizumab in Monotherapy or in Combination With Nonbiologic Disease-Modifying Antirheumatic Drugs in Latin American Patients With Moderate to Severe Active Rheumatoid Arthritis

Mysler, Eduardo, Cardiel, Mario H., Xavier, Ricardo M., LÃ³pez, Alejandra, Ramos-Esquivel, Allan

Journal:

JCR Journal of Clinical Rheumatology

Year:

2020

File:

PDF, 1.08 MB

2020

37

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12â15 June 2019 - ()] Spondyloarthritis â treatment - FRI0400âLONG-TERM SAFETY OF IXEKIZUMAB IN PATIENTS WITH RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS/ANKYLOSING SPONDYLITIS: AN INTEGRATED ANALYSIS OF COAST-V AND COAST-W

Marzo-Ortega, Helena, Mysler, Eduardo, Tomita, Tetsuya, Lisse, Jeffrey, Santisteban, Silvia, Garces, Sandra, Xu, Wen, Rudwaleit, Martin, Salvarani, Carlo, Schwartzman, Sergio

Year:

2019

File:

PDF, 523 KB

2019

38

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12â15 June 2019 - ()] Poster Presentations - THU0188âINHIBITION OF STRUCTURAL JOINT DAMAGE WITH UPADACITINIB AS MONOTHERAPY OR IN COMBINATION WITH METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS: 1 YEAR OUTCOMES FROM THE SELECT PHASE 3 PROGRAM

Peterfy, Charles, Genovese, Mark C., Song, In-Ho, Friedman, Alan, Hall, Stephen, Mysler, Eduardo, Durez, Patrick, Baraliakos, Xenofon, Enejosa, Jose Jeffrey, Shaw, Tim, Yihan, LI, Chen, Su, Strand, Vi

Year:

2019

File:

PDF, 651 KB

2019

39

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12â15 June 2019 - ()] Poster Presentations - THU0174âCHARACTERIZATION OF REMISSION IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH UPADACITINIB OR COMPARATORS

Hall, Stephen, Takeuchi, Tsutomu, Thomson, Glen, Emery, Paul, Combe, Bernard, Everding, Andrea, Pavelka, Karel, Song, Yanna, Shaw, Tim, Friedman, Alan, Song, In-Ho, Mysler, Eduardo

Year:

2019

File:

PDF, 632 KB

2019

40

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12â15 June 2019 - ()] Poster Presentations - FRI0147âSAFETY AND EFFECTIVENESS OF UPADACITINIB OR ADALIMUMAB IN PATIENTS WITH RHEUMATOID ARTHRITIS: RESULTS AT 48 WEEKS FROM THE SELECT-COMPARE STUDY

Fleischmann, Roy, Enejosa, Jeffrey, Song, In-Ho, Mysler, Eduardo, Bessette, Louis, Peterfy, Charles, Durez, Patrick, Ostor, Andrew, Yihan, LI, Zhou, Yijie, Genovese, Mark C.

Year:

2019

File:

PDF, 590 KB

2019

41

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12â15 June 2019 - ()] Poster Presentations - THU0193âEFFICACY OF TOFACITINIB MONOTHERAPY, TOFACITINIB WITH METHOTREXATE AND ADALIMUMAB WITH METHOTREXATE IN PATIENTS WITH EARLY (â¤2 YEARS) VS ESTABLISHED (>2 YEARS) RHEUMATOID ARTHRITIS: A POST HOC ANALYSIS OF DATA FROM ORAL STRATEGY

Takeuchi, Tsutomu, Tanaka, Yoshiya, Sugiyama, Naonobu, Iikuni, Noriko, Soma, Koshika, Shi, Harry, Mysler, Eduardo, Moots, Robert J, Smolen, Josef S., Fleischmann, Roy

Year:

2019

File:

PDF, 1.41 MB

2019

42

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12â15 June 2019 - ()] Poster Presentations - THU0102âPATIENT DISEASE TRAJECTORIES IN BARICITINIB-TREATED PATIENTS WITH RHEUMATOID ARTHRITIS AND INADEQUATE RESPONSE TO METHOTREXATE

Taylor, Peter C., Emery, Paul, Weinblatt, Michael E., Mysler, Eduardo, Rubbert-Roth, Andrea, Jia, Bochao, Sun, Luna, Liu, Yushi, Chen, Yun-Fei, Cardoso, Anabela, Tanaka, Yoshiya

Year:

2019

File:

PDF, 699 KB

2019